• Katherine’s honeymoon got off to a bumby start when she forgot her passport. The couple had to stop over in California, instead of going directly to Cabo.

• Katherine’s co-stars from Grey’s Anatomy that attended her wedding were T.R. Knight, Sandra Oh, and Kate Walsh.

• Katherine’s best man in her wedding was her Grey’s Anatomy co-star T.R. Knight.

• Katherine married musician Josh Kelley in Park City ceremony witnessed by her Grey’s Anatomy co-stars.

• Katherine participated in the picketers’ line in the 2007 Writers Guild Of America’s strike.

• Katherine has said that filming the birthing scenes in the 2007 film Knocked Up helped seal her decision to adopt children, rather than conceive on her own. “It doesn’t sound like any fun to me,” she says.

• Katherine received the role of Alison in Knocked Up after actress Anne Hathaway, who was originally offered the part, backed out due to the graphic birthing scenes.

• In Wish Upon a Star, Katherine is more than a year younger than Danielle Harris, who plays her younger sister in the movie.

• In June 2007, Katherine launched her own line of hospital scrubs and hospital gear from the Katherine Heigl Collection. Katherine collaborated with a health-care clothing company to design the line.

• Katherine says that T.R. Knight (co-star on Grey’s Anatomy) is her best friend.

• When Katherine had to do her first underwear scene in Grey’s Anatomy she felt very uncomfortable. She jokingly asked the director to strip down as well, and he obliged!

• Katherine’s favorite movie is The 40 Year Old Virgin, which she watches over and over again.

• Katherine says that her Grey’s Anatomy co-star Justin Chambers is like a brother to her. The whole crew has become her family.

• Katherine enjoys relaxing, sitting on one of her big couches with her dogs, reading, knitting, or going to the movies or bar with her fiance.

• Katherine was honored by Cosmopolitan magazine and had dinner with the magazine’s editor, Kate White, to celebrate her appearance on the cover of Cosmopolitan’s December 2006 issue.

• Katherine’s fiancé, singer Josh Kelley, proposed to her in June 2006 with a three-carat pear-shaped diamond engagement ring. Josh and Katherine met on the set of his music video for the song ‘Only You,’ which Katherine appeared in. The pair is planning a “Winter Wonderland” themed wedding.

• Rather than see a stylist, Katherine cut and dyed her own hair for the third season of Roswell.

• She has two miniature schnauzers named Anna and Romeo.

• During high school, Katherine played the cello.

• Katherine’s brother Jason died when she was young, due to head injuries sustained in a car accident.

• Katherine beat out Alicia Silverstone for the lead role in My Father the Hero.

• Katherine graduated from New Canaan High School in 1996.

• She began dating Joseph Lawrence in 1994. They met at Seventeen Magazine’s 50th Anniversary party.

• Katherine is half Irish and half German.

• Katherine auditioned for all three female leads on Roswell (Isabel, Maria, and Liz) before she was cast as Isabel.

• Katherine has two older brothers named Holt and Jason. She also has an older sister named Meg.

• Katherine is a former client of the Elite Modelling Agency.

• Katherine was honored by the National Coalition on Donation Awards in July 2005 in Los Angeles. She received the James S. Wolf Courage Award for educating the public about organ donation.

• Katherine was once engaged to Jason Behr, her former Roswell co-star. They broke up in 2001.

• Katherine has played three separate characters with the same name (although one time, it had a slightly different spelling). In Roswell, she was Isabel Evans. In Wuthering Heights, she played an Isabel once again. In Grey’s Anatomy, she plays Isobel.